Article
Prolactin concentrations during aripiprazole treatment in relation to sex, plasma drugs concentrations and genetic polymorphisms of dopamine D2 receptor and cytochrome P450 2D6 in Japanese patients with schizophrenia.
Psychiatry and clinical neurosciences - 1 Oct 2012
Nagai Goyo, Mihara Kazuo, Nakamura Akifumi, Suzuki Takeshi, Nemoto Kenji, Kagawa Shoko, Ohta Ikuya, Arakaki Hajime, Kondo Tsuyoshi
Abstract excerpt
AIMS: The authors investigated the correlation between prolactin concentrations during aripiprazole treatment and various factors, including age, sex, plasma concentrations of aripiprazole and its active metabolite, dehydroaripiprazole, and genetic polymorphisms of dopamine D2 receptor (DRD2) and cytochrome P450(CYP)2D6. METHODS: The subjects were 70 inpatients with schizophrenia (36 men and 34 women), receiving...
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