Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The influence of aging and estradiol to progesterone ratio on rat macrophage phenotypic profile and NO and TNF-α production.

Experimental gerontology - 1 Nov 2013

Dimitrijević Mirjana, Stanojević Stanislava, Kuštrimović Nataša, Mitić Katarina, Vujić Vesna, Aleksić Iva, Radojević Katarina, Leposavić Gordana

Abstract excerpt

The phenotype and function of tissue macrophages substantially depend on the cellular milieu and biological effector molecules, such as steroid hormones, to which they are exposed. Furthermore, in female rats, aging is associated with the altered macrophage functioning and the increased estrogen level is followed by a decrease in that of progesterone. Therefore, the present study aimed to investigate the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antigens, Differentiation, Myelomonocytic
Share to CD163 Antigen

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Estradiol

Share to Inflammation Mediators

Share to Macrophages, Peritoneal

Share to Nitric Oxide

Share to Ovariectomy

Share to Progesterone

Source

Identifiers

PMID: 23850866
DOI: 10.1016/j.exger.2013.07.001

Genes

TNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The influence of aging and estradiol to progesterone ratio on rat macrophage phenotypic profile and NO and TNF-α production.PMID 23850866Read ↗

Self-renewal and phenotypic conversion are the main physiological responses of macrophages to the endogenous estrogen surge.Semantic proximity Read ↗

The estrogen–macrophage interplay in the homeostasis of the female reproductive tractSemantic proximity Read ↗

Macrophage function and polarization in cardiovascular disease: a role of estrogen signaling?Semantic proximity Read ↗

Cell Line-Specific Estrogen Responses Uncover Functional Sex Differences in Murine MacrophagesSemantic proximity Read ↗

Metabololipidomic and proteomic profiling reveals aberrant macrophage activation and interrelated immunomodulatory mediator release during agingSemantic proximity Read ↗

ERα-independent NRF2-mediated immunoregulatory activity of tamoxifenSemantic proximity Read ↗

Menopause leads to elevated expression of macrophage-associated genes in the aging frontal cortex: rat and human studies identify strikingly similar changesSemantic proximity Read ↗

Effect of aging on the female reproductive functionSemantic proximity Read ↗

ERα-independent NRF2-mediated immunoregulatory activity of tamoxifen.Semantic proximity Read ↗

Advanced Age Impairs Macrophage PolarizationSemantic proximity Read ↗

Phenotypic and functional differences between rat alveolar, pleural, and peritoneal macrophages.Semantic proximity Read ↗

Macrophages from naked mole-rat possess distinct immunometabolic signatures upon polarization.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.