Article
Cardiac expression of Brn-3a and Brn-3b POU transcription factors and regulation of Hsp27 gene expression.
Cell stress & chaperones - 1 Sept 2008
Farooqui-Kabir Saleha R, Diss James K J, Henderson Deborah, Marber Michael S, Latchman David S, Budhram-Mahadeo Vishwanie, Heads Richard J
Abstract excerpt
The Brn-3 family of transcription factors play a critical role in regulating expression of genes that control cell fate, including the small heat shock protein Hsp27. The aim of this study was to investigate the relationship between Brn-3a and Brn-3b and Hsp27 expression in the developing rodent heart. Brn-3a and Brn-3b were detected from embryonic days 9.5-10.5 (E9.5-E10.5) in the mouse heart, with significant...
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