Article
Arginase-1 mRNA expression correlates with myeloid-derived suppressor cell levels in peripheral blood of NSCLC patients.
Lung cancer (Amsterdam, Netherlands) - 1 Sept 2013
Heuvers Marlies E, Muskens Femke, Bezemer Koen, Lambers Margaretha, Dingemans Anne-Marie C, Groen Harry J M, Smit Egbert F, Hoogsteden Henk C, Hegmans Joost P J J, Aerts Joachim G J V
Abstract excerpt
Myeloid-derived suppressor cells (MDSC) are a heterogeneous population of immature and progenitor myeloid cells with immunosuppressive activity that are increased in cancer patients. Until now, the characterization of MDSC in humans was very challenging. The aim of this study was to determine the...
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