Article
The effects of CX3CR1 deficiency and irradiation on the homing of monocyte-derived cell populations in the mouse eye.
PloS one - 1 Jan 2013
Kezic Jelena M, McMenamin Paul G
Abstract excerpt
This study examined whether CX3CR1 deficiency altered monocytic cell replenishment dynamics in ocular tissues in the context of radiation chimeras. Long-term effects of irradiation and effects of sublethal irradiation on ocular macrophages were also assessed. Bone marrow from BALB/c Cx 3 cr1 (+/gfp) or Cx 3 cr1 (gfp/gfp) mice was used to reconstitute full body irradiated WT mice and donor cell densities in the...
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