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Article

Rapid Cl⁻/HCO⁻₃exchange kinetics of AE1 in HEK293 cells and hereditary stomatocytosis red blood cells.

American journal of physiology. Cell physiology - 15 Sept 2013

Frumence Etienne, Genetet Sandrine, Ripoche Pierre, Iolascon Achille, Andolfo Immacolata, Le Van Kim Caroline, Colin Yves, Mouro-Chanteloup Isabelle, Lopez Claude

Abstract excerpt

Anion exchanger 1 (AE1) or band 3 is a membrane protein responsible for the rapid exchange of chloride for bicarbonate across the red blood cell membrane. Nine mutations leading to single amino-acid substitutions in the transmembrane domain of AE1 are associated with dominant hereditary stomatocytosis, monovalent cation leaks, and reduced anion exchange activity. We set up a stopped-flow spectrofluorometry assay...

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Identifiers

PMID: 23842529
DOI: 10.1152/ajpcell.00142.2013

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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