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Article

Trafficking defects of the Southeast Asian ovalocytosis deletion mutant of anion exchanger 1 membrane proteins.

The Biochemical journal - 15 Dec 2005

Cheung Joanne C, Cordat Emmanuelle, Reithmeier Reinhart A F

Abstract excerpt

Human AE1 (anion exchanger 1) is a membrane glycoprotein found in erythrocytes and as a truncated form (kAE1) in the BLM (basolateral membrane) of a-intercalated cells of the distal nephron, where they carry out electroneutral chloride/bicarbonate exchange. SAO (Southeast Asian ovalocytosis) is a dominant inherited haematological condition arising from deletion of Ala400-Ala408 in AE1, resulting in a misfolded...

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Share to Elliptocytosis, Hereditary

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Source

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Identifiers

PMID: 16107207
DOI: 10.1042/BJ20051076
PMCID: PMC1316280

Genes

BLM

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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