Article
Band 3, the human red cell chloride/bicarbonate anion exchanger (AE1, SLC4A1), in a structural context.
Biochimica et biophysica acta - 1 Jul 2016
Reithmeier Reinhart A F, Casey Joseph R, Kalli Antreas C, Sansom Mark S P, Alguel Yilmaz, Iwata So
Abstract excerpt
The crystal structure of the dimeric membrane domain of human Band 3(1), the red cell chloride/bicarbonate anion exchanger 1 (AE1, SLC4A1), provides a structural context for over four decades of studies into this historic and important membrane glycoprotein. In this review, we highlight the key structural features responsible for anion binding and translocation and have integrated the following topological...
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