Article
TNFRSF10B polymorphisms and haplotypes associated with increased risk of death in non-small cell lung cancer.
Carcinogenesis - 1 Nov 2013
Schabath Matthew B, Giuliano Anna R, Thompson Zachary J, Amankwah Ernest K, Gray Jhanelle E, Fenstermacher David A, Jonathan Kristen A, Beg Amer A, Haura Eric B
Abstract excerpt
Presently, there are few validated biomarkers that can predict survival or treatment response for non-small cell lung cancer (NSCLC) and most are based on tumor markers. Biomarkers based on germ line DNA variations represent a valuable complementary strategy, which could have translational implications by subclassifying patients to tailored, patient-specific treatment. We analyzed single nucleotide polymorphisms...
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