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Article

Haplotypes covering the TNFSF10 gene are associated with bronchial asthma.

Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology - 1 Feb 2011

Weckmann Markus, Kopp Matthias Volkmar, Heinzmann Andrea, Mattes Joerg

Abstract excerpt

Tumour necrosis factor-related apoptosis-inducing ligand (TRAIL) is elevated in the airways of subjects with asthma and has been linked to the development of allergic airway disease by promoting STAT6-dependent T helper 2 cell (T(H) 2) effector functions. To determine whether single nucleotide polymorphisms (SNPs) in the TNFSF10 gene are associated with bronchial asthma we genotyped 498 Caucasian subjects living...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 20961336
DOI: 10.1111/j.1399-3038.2010.01027.x

Genes

TNFSF10
STAT6

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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