Article
Genetic variants in cytokine signaling pathways and clinical outcomes in early-stage lung cancer patients.
The Journal of thoracic and cardiovascular surgery - 1 Jun 2018
Sepesi Boris, Ye Yuanqing, Mitchell Kyle G, Zhang Liren, Gu Jianchun, Ji Lin, Antonoff Mara B, Hofstetter Wayne L, Rice David C, Mehran Reza J, Walsh Garrett L, Vaporciyan Ara A, Swisher Stephen G, Roth Jack A, Wu Xifeng
Abstract excerpt
OBJECTIVES: The purpose of this study was to explore the role of single nucleotide polymorphisms (SNPs) in cytokine signaling genes and to compare them with clinical outcomes in surgical patients with non-small cell lung cancer (NSCLC). METHODS: SNPs of the cytokine signaling pathway were analyzed using peripheral blood of 722 patients who underwent resection of stage I to III NSCLC between 1995 and 2009. Cox...
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