Article
Predictors of survival in never-smokers with non-small cell lung cancer: a large-scale, two-phase genetic study.
Clinical cancer research : an official journal of the American Association for Cancer Research - 1 Nov 2012
Pu Xia, Ye Yuanqing, Spitz Margaret R, Wang Liang, Gu Jian, Lippman Scott M, Hildebrandt Michelle A T, Hong Waun Ki, Minna John D, Roth Jack A, Yang Ping, Wu Xifeng
Abstract excerpt
PURPOSE: Lung cancer in never-smokers (LCINS) is increasingly recognized as a distinct disease from that in ever-smokers owing to substantial differences in etiology, clinical characteristics, and prognosis. Therefore, we aimed to identify prognostic markers specific for LCINS. EXPERIMENTAL DESIGN: First, 11,930 single-nucleotide polymorphisms (SNP) in 904 inflammation-related genes were genotyped, and their...
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