Functional diversity of the glutathione peroxidase gene family among human populations: implications for genetic predisposition to disease and drug response.

doi:10.2217/pgs.13.99

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Article

Functional diversity of the glutathione peroxidase gene family among human populations: implications for genetic predisposition to disease and drug response.

Pharmacogenomics - 1 Jul 2013

Polimanti Renato, Fuciarelli Maria, Destro-Bisol Giovanni, Battaggia Cinzia

Abstract excerpt

AIM: To analyze the human genetic variation of glutathione peroxidases (GPX), estimating the functional differences among human populations and suggesting interethnic differences in predisposition to disease and drug response. MATERIALS & METHODS: Using 1000 Genomes Project data, we analyzed 723 GPX variants in 1092 individuals belonging to 14 populations. Combining functional prediction analyses of coding and...

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Identifiers

PMID: 23837478
DOI: 10.2217/pgs.13.99

Genes

GPX1
GPX3

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.