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Article

Polymorphism analysis of six selenoprotein genes: support for a selective sweep at the glutathione peroxidase 1 locus (3p21) in Asian populations.

BMC genetics - 11 Dec 2006

Foster Charles B, Aswath Kshama, Chanock Stephen J, McKay Heather F, Peters Ulrike

Abstract excerpt

BACKGROUND: There are at least 25 human selenoproteins, each characterized by the incorporation of selenium into the primary sequence as the amino acid selenocysteine. Since many selenoproteins have antioxidant properties, it is plausible that inter-individual differences in selenoprotein expression or activity could influence risk for a range of complex diseases, such as cancer, infectious diseases as well as...

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Source

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Identifiers

PMID: 17156480
DOI: 10.1186/1471-2156-7-56
PMCID: PMC1769511

Genes

GPX1
GPX2
GPX3
GPX4
TXNRD1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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