Article
Changes in vimentin, lamin A/C and mitofilin induce aberrant cell organization in fibroblasts from Fanconi anemia complementation group A (FA-A) patients.
Biochimie - 1 Oct 2013
Capanni Cristina, Bruschi Maurizio, Columbaro Marta, Cuccarolo Paola, Ravera Silvia, Dufour Carlo, Candiano Giovanni, Petretto Andrea, Degan Paolo, Cappelli Enrico
Abstract excerpt
Growing number of publication has proved an increasing of cellular function of the Fanconi anemia proteins. To chromosome stability and DNA repair new roles have been attributed to FA proteins in oxidative stress response and homeostasis, immune response and cytokines sensibility, gene expression. Our work shows a new role for FA-A protein: the organization of the cellular structure. By 2D-PAGE of FA-A and...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
