Article
Spectrin changes occur in erythrocytes from patients with Fanconi's anemia and their parents.
Biochemical and biophysical research communications - 14 Jul 2000
Straface E, Masella R, Del Principe D, Franceschi C, Korkina L G, Zatterale A, Pagano G, Malorni W
Abstract excerpt
Fanconi's anemia (FA) is a clinically and genetically heterogeneous disease which has been hypothesized to be defective in the detoxification of reactive oxygen species. In this work we report the results obtained by morphometric analyses on the red blood cells (RBCs) from FA patients and their parents. We found that a high rate of erythrocytes from both homozygous and heterozygous subjects was significantly...
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