Article
Association of ATP-binding cassette transporter variants with the risk of Alzheimer's disease.
Pharmacogenomics - 1 Apr 2013
Cascorbi Ingolf, Flüh Charlotte, Remmler Cornelia, Haenisch Sierk, Faltraco Frank, Grumbt Maria, Peters Michele, Brenn Anja, Thal Dietmar Rudolf, Warzok Rolf Wolfgang, Vogelgesang Silke
Abstract excerpt
AIM: A number of studies have demonstrated that ABCB1 and BCRP (ABCG2) actively transport Aβ. We aimed to investigate the association of genetic variants of selected multidrug transporters with Alzheimer's disease (AD) in histopathologically confirmed AD cases and controls. MATERIALS & METHODS: D...
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