Article
Coding Variants are Relevant to the Expression of Obesity-Related Genes for Pediatric Adiposity.
Obesity (Silver Spring, Md.) - 1 Jan 2021
Mao Ke, Zhang Meixian, Cao Jinshuai, Zhao Xiaoyuan, Gao Liwang, Fu Liwan, Cheng Hong, Yan Chun, Xu Xiaopeng, Shi Xiaofeng, Jiang Zhuoyuan, Wang Bingqing, Zhang Yong-Biao, Mi Jie
Abstract excerpt
OBJECTIVE: Heredity has a remarkable effect on obesity in an obesogenic environment. Despite the numerous genetic variants that contribute to obesity-related traits, none has been identified in Chinese children. This study aimed to identify novel variants associated with childhood obesity in China. METHODS: Promising single-nucleotide variants were obtained using whole-exome sequencing from 76 children who had...
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