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Article

Methods to examine the impact of nonsynonymous SNPs on protein degradation and function of human ABC transporter.

Methods in molecular biology (Clifton, N.J.) - 1 Jan 2013

Ishikawa Toshihisa, Wakabayashi-Nakao Kanako, Nakagawa Hiroshi

Abstract excerpt

Clinical studies have strongly suggested that genetic polymorphisms and/or mutations of certain ATP-binding cassette (ABC) transporter genes might be regarded as significant factors affecting patients' responses to medication and/or the risk of diseases. In the case of ABCG2, certain single nucleotide polymorphisms (SNPs) in the encoding gene alter the substrate specificity and/or enhance endoplasmic...

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Share to ATP Binding Cassette Transporter, Subfamily G, Member 2
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Endoplasmic Reticulum-Associated Degradation

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Source

Identifiers

PMID: 23824860
DOI: 10.1007/978-1-62703-435-7_15

Genes

ABCG2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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