Article
SCAN: a systems biology approach to pharmacogenomic discovery.
Methods in molecular biology (Clifton, N.J.) - 1 Jan 2013
Gamazon Eric R, Huang R Stephanie, Cox Nancy J
Abstract excerpt
Genome-wide association (GWA) studies have identified thousands of genetic variants that contribute to disease and pharmacologic traits. More recently, high-throughput sequencing studies promise to provide a more complete catalog of genetic variants with roles in human phenotypic variation. Yet, characterizing the influence of functional variants on genes, RNAs, proteins, and ultimately disease or pharmacologic...
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