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Flaviviruses Are Sensitive to Inhibition of Thymidine Synthesis Pathways

4 Jul 2013

Abstract excerpt

Dengue virus has emerged as a global health threat to over one-third of humankind. As a positive-strand RNA virus, dengue virus relies on the host cell metabolism for its translation, replication, and egress. Therefore, a better understanding of the host cell metabolic pathways required for dengue virus infection offers the opportunity to develop new approaches for therapeutic intervention. In a recently...

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PMID: 23824813
DOI: 10.1128/jvi.00101-13

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