Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Mechanism of Action of Methotrexate Against Zika Virus

10 Apr 2019

Abstract excerpt

Zika virus (ZIKV), which is associated with microcephaly in infants and Guillain-Barré syndrome, reemerged as a serious public health threat in Latin America in recent years. Previous high-throughput screening (HTS) campaigns have revealed several potential hit molecules against ZIKV, including methotrexate (MTX), which is clinically used as an anti-cancer chemotherapy and anti-rheumatoid agent. We studied the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Mosquito-borne diseases and control

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 30974762
DOI: 10.3390/v11040338

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Mechanism of Action of Methotrexate Against Zika VirusPMID 30974762Read ↗

Zika antiviral chemotherapy: identification of drugs and promising starting points for drug discovery from an FDA-approved librarySemantic proximity Read ↗

Repurposing of Doramectin as a New Anti-Zika Virus AgentSemantic proximity Read ↗

Development of Small-Molecule Inhibitors Against Zika Virus InfectionSemantic proximity Read ↗

Development of a replicon cell line-based high throughput antiviral assay for screening inhibitors of Zika virusSemantic proximity Read ↗

Identification of Novel Natural Products as Effective and Broad-Spectrum Anti-Zika Virus InhibitorsSemantic proximity Read ↗

Zika Virus Replicons for Drug DiscoverySemantic proximity Read ↗

Zika virus infection reprograms global transcription of host cells to allow sustained infectionSemantic proximity Read ↗

Therapeutics for flaviviral infectionsSemantic proximity Read ↗

Zika Virus: Where Is the Treatment?Semantic proximity Read ↗

Importance of Zika Virus NS5 Protein for Viral ReplicationSemantic proximity Read ↗

The clinically approved antiviral drug sofosbuvir inhibits Zika virus replication.Semantic proximity Read ↗

Fangchinoline Inhibits Zika Virus by Disrupting Virus InternalizationSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.