Article
Preneoplastic lesions induced by myc and src oncogenes in reconstituted mouse bladder.
Surgery - 1 Aug 1990
Wagner H E, Steele G, Summerhayes I C
Abstract excerpt
To define a role for different oncogenes in bladder neoplastic progression we have introduced viral myc and src oncogenes, singly or in combination, into intact normal urothelium. After incubation with virus, infected mucosa was heterotransplanted under the renal capsule of syngeneic animals and...
Topics
- Animals
- Epithelium
- Genes, Viral
- Kidney
- Mice
- Mice, Inbred C57BL
- Oncogene Proteins, Viral
- Oncogenes
- Phenotype
- Precancerous Conditions
- Urinary Bladder
- Urinary Bladder Neoplasms
- Virus Diseases