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Article

Characterization at nucleotide resolution of the homogeneously staining region sites of insertion in two cancer cell lines.

Nucleic acids research - 1 Sept 2013

Gibaud Anne, Vogt Nicolas, Brison Olivier, Debatisse Michelle, Malfoy Bernard

Abstract excerpt

The mechanisms of formation of intrachromosomal amplifications in tumours are still poorly understood. By using quantitative polymerase chain reaction, DNA sequencing, chromosome walking, in situ hybridization on metaphase chromosomes and whole-genome analysis, we studied two cancer cell lines containing an MYC oncogene amplification with acquired copies ectopically inserted in rearranged chromosomes 17. These...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Chromosomes, Human, Pair 17

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Source

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Identifiers

PMID: 23821669
DOI: 10.1093/nar/gkt566
PMCID: PMC3783161

Genes

MYC

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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