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Article

Ceragenin CSA-13 induces cell cycle arrest and antiproliferative effects in wild-type and p53 null mutant HCT116 colon cancer cells.

Anti-cancer drugs - 1 Sept 2013

Kuroda Kengo, Fukuda Tomokazu, Okumura Kazuhiko, Yoneyama Hiroshi, Isogai Hiroshi, Savage Paul B, Isogai Emiko

Abstract excerpt

Antimicrobial peptides of the cathelicidin family play a central role in the host defense system. Our group has reported previously that cathelicidin-related or cathelicidin-modified antimicrobial peptides, such as FF/CAP-18, have antiproliferative effects on the squamous cell carcinoma cell line SAS-H1 and colon cancer-derived cell line HCT116. Ceragenin CSA-13, which mimics the hydrophobic and cationic...

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PMID: 23817390
DOI: 10.1097/CAD.0b013e3283634dd0

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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