Article
Crocetin induces cytotoxicity in colon cancer cells via p53-independent mechanisms.
Asian Pacific journal of cancer prevention : APJCP - 1 Jan 2012
Li Cai-Yan, Huang Wen-Feng, Wang Qun-Li, Wang Fan, Cai E, Hu Bing, Du Jia-Cheng, Wang Jing, Chen Rong, Cai Xiao-Jing, Feng Jing, Li Hui-Hui
Abstract excerpt
OBJECTIVE: Crocin has been proposed as a promising candidate for cancer chemoprevention. The purpose of this investigation was to investigate the chemopreventive action and the possible mechanisms of crocin against human colon cancer cells in vitro. METHODS: Cell proliferation was examined using MTT assay and the cell cycle distribution fractions were analyzed using flow cytometric analysis after propidium iodide...
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