Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Smad2 and Myocardin-Related Transcription Factor B Cooperatively Regulate Vascular Smooth Muscle Differentiation From Neural Crest Cells

2 Jul 2013

Abstract excerpt

RATIONALE: Vascular smooth muscle cell (VSMC) differentiation from neural crest cells (NCCs) is critical for cardiovascular development, but the mechanisms remain largely unknown. OBJECTIVE: Transforming growth factor-β (TGF-β) function in VSMC differentiation from NCCs is controversial. Therefore, we determined the role and mechanism of a TGF-β downstream signaling intermediate Smad2 in NCC differentiation to...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Congenital gastrointestinal and neural anomalies
Share to Congenital heart defects research
Share to TGF-β signaling in diseases

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 23817199
DOI: 10.1161/circresaha.113.301921

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Smad2 and Myocardin-Related Transcription Factor B Cooperatively Regulate Vascular Smooth Muscle Differentiation From Neural Crest CellsPMID 23817199Read ↗

Smooth Muscle Cells Derived From Second Heart Field and Cardiac Neural Crest Reside in Spatially Distinct Domains in the Media of the Ascending Aorta-Brief Report.Semantic proximity Read ↗

Myocardin-related transcription factor B is required for normal mouse vascular development and smooth muscle gene expression.Semantic proximity Read ↗

Differentiation defect in neural crest-derived smooth muscle cells in patients with aortopathy associated with bicuspid aortic valves.Semantic proximity Read ↗

Transforming Growth Factor-β and Notch Signaling Mediate Stem Cell Differentiation into Smooth Muscle CellsSemantic proximity Read ↗

Heterogeneous Cardiac- and Neural Crest-Derived Aortic Smooth Muscle Cells have Similar Transcriptional Changes after TGFβ Signaling DisruptionSemantic proximity Read ↗

The Cardiac Neural Crest Cells in Heart Development and Congenital Heart DefectsSemantic proximity Read ↗

Derivation of Smooth Muscle Cells with Neural Crest Origin from Human Induced Pluripotent Stem CellsSemantic proximity Read ↗

Requirement of myocardin-related transcription factor-B for remodeling of branchial arch arteries and smooth muscle differentiation.Semantic proximity Read ↗

Endothelial to Mesenchymal Transition in the Cardiogenesis and Cardiovascular DiseasesSemantic proximity Read ↗

Smooth muscle stem cellsSemantic proximity Read ↗

Cooperation of myocardin and smad2 in inducing differentiation of mesenchymal stem cells into smooth muscle cellsSemantic proximity Read ↗

Smooth Muscle Cell-Specific TGFβ2 Protects Against Thoracic Aortic Aneurysm and Dissection in MiceSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.