Article
Point mutation is responsible for Arabidopsis tz-201 mutant phenotype affecting thiamin biosynthesis.
Plant & cell physiology - 1 Aug 2003
Papini-Terzi Flávia Stal, Galhardo Rodrigo Silva, Farias Leonardo Paiva, Menck Carlos Frederico Martins, Van Sluys Marie-Anne
Abstract excerpt
A point mutation in the thi1 gene, involved in the synthesis of thiamin, has been identified in a tz-201 mutant line of Arabidopsis thaliana. The mutation occurs in a conserved protein domain and prevents the mutant plants from synthesizing thiamin. Complementation assays in yeast thi4 mutant confirm that this mutation hinders thiamin synthesis and, thus, is responsible for the tz phenotype. Northern blot...
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