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Article

Nucleophosmin gene mutations are predictors of favorable prognosis in acute myelogenous leukemia with a normal karyotype.

Blood - 1 Dec 2005

Schnittger Susanne, Schoch Claudia, Kern Wolfgang, Mecucci Cristina, Tschulik Claudia, Martelli Massimo F, Haferlach Torsten, Hiddemann Wolfgang, Falini Brunangelo

Abstract excerpt

Nucleophosmin (NPM1) exon-12 gene mutations are the hallmark of a large acute myelogenous leukemia (AML) subgroup with normal karyotype, but their prognostic value in this AML subset has not yet been determined. We screened 401 AML patients with normal karyotype treated within the German AML Coop...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 16076867
DOI: 10.1182/blood-2005-06-2248

Genes

FLT3
NPM1
EFS
KIT
NRAS

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-16076867-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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