Article
Length polymorphism in heme oxygenase-1 and risk of CKD among patients with coronary artery disease.
Journal of the American Society of Nephrology : JASN - 1 Nov 2014
Chen Yu-Hsin, Kuo Ko-Lin, Hung Szu-Chun, Hsu Chih-Cheng, Chen Ying-Hwa, Tarng Der-Cherng
Abstract excerpt
The length polymorphism of guanosine thymidine dinucleotide repeats in the heme oxygenase-1 gene promoter is associated with cardiovascular events and mortality in high-risk populations. Experimental data suggest that heme oxygenase-1 protects against kidney disease. However, the association between this polymorphism and long-term risk of CKD in high-risk patients is unknown. We analyzed the allelic frequencies...
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