Article
Subunit composition and kinetics of the Renshaw cell heteromeric nicotinic receptors.
Biochemical pharmacology - 15 Oct 2013
Lamotte d'Incamps Boris, Ascher Philippe
Abstract excerpt
In Renshaw cells (RCs) of newborn mice, activation of motoneurons elicits a four-component synaptic current (EPSC) mediated by two glutamate receptors and two nicotinic receptors (nAChRs). We have analyzed the nicotinic component of the EPSC which is blocked by dihydro-beta-erythroidine (DHβE) with the dual objective of identifying the nAChR subunits involved and of understanding the kinetics of the response. The...
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