Article
Diversifying microRNA sequence and function.
Nature reviews. Molecular cell biology - 1 Aug 2013
Ameres Stefan L, Zamore Phillip D
Abstract excerpt
MicroRNAs (miRNAs) regulate the expression of most genes in animals, but we are only now beginning to understand how they are generated, assembled into functional complexes and destroyed. Various mechanisms have now been identified that regulate miRNA stability and that diversify miRNA sequences to create distinct isoforms. The production of different isoforms of individual miRNAs in specific cells and tissues...
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