Article
Complexity of microRNA function and the role of isomiRs in lipid homeostasis.
Journal of lipid research - 1 May 2013
Vickers Kasey C, Sethupathy Praveen, Baran-Gale Jeanette, Remaley Alan T
Abstract excerpt
MicroRNAs (miRNAs) are key posttranscriptional regulators of biological pathways that govern lipid metabolic phenotypes. Recent advances in high-throughput small RNA sequencing technology have revealed the complex and dynamic repertoire of miRNAs. Specifically, it has been demonstrated that a single genomic locus can give rise to multiple, functionally distinct miRNA isoforms (isomiR). There are several...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
