Article
miRNA Nomenclature: A View Incorporating Genetic Origins, Biosynthetic Pathways, and Sequence Variants.
Trends in genetics : TIG - 1 Nov 2015
Desvignes T, Batzel P, Berezikov E, Eilbeck K, Eppig J T, McAndrews M S, Singer A, Postlethwait J H
Abstract excerpt
High-throughput sequencing of miRNAs has revealed the diversity and variability of mature and functional short noncoding RNAs, including their genomic origins, biogenesis pathways, sequence variability, and newly identified products such as miRNA-offset RNAs (moRs). Here we review known cases of alternative mature miRNA-like RNA fragments and propose a revised definition of miRNAs to encompass this diversity. We...
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