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Article

Diagnosis of prostate cancer by detection of minichromosome maintenance 5 protein in urine sediments

20 Jul 2010

Abstract excerpt

BACKGROUND: The accuracy of prostate-specific antigen (PSA) testing in prostate cancer detection is constrained by low sensitivity and specificity. Dysregulated expression of minichromosome maintenance (Mcm) 2-7 proteins is an early event in epithelial multistep carcinogenesis and thus MCM proteins represent powerful cancer diagnostic markers. In this study we investigate Mcm5 as a urinary biomarker for prostate...

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Share to Genomic variations and chromosomal abnormalities
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PMID: 20648010
DOI: 10.1038/sj.bjc.6605785

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