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Article

Reduced susceptibility to two-stage skin carcinogenesis in mice with epidermis-specific deletion of CD151.

The Journal of investigative dermatology - 1 Jan 2014

Sachs Norman, Secades Pablo, van Hulst Laura, Song Ji-Ying, Sonnenberg Arnoud

Abstract excerpt

Altered expression of the tetraspanin CD151 is associated with skin tumorigenesis; however, whether CD151 is causally involved in the tumorigenic process is not known. To evaluate its role in tumor formation, we subjected epidermis-specific Cd151 knockout mice to chemical skin carcinogenesis. Mice lacking epidermal Cd151 developed fewer and smaller tumors than wild-type mice after treatment with...

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Source

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Identifiers

PMID: 23792458
DOI: 10.1038/jid.2013.280
PMCID: PMC4570276

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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