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Article

Human papillomavirus 16 E5 oncogene contributes to two stages of skin carcinogenesis.

Cancer research - 1 Jul 2007

Maufort John P, Williams Sybil M Genther, Pitot Henry C, Lambert Paul F

Abstract excerpt

High-risk human papillomaviruses (HPVs), which cause the vast majority of cervical cancer, other anogenital cancers, and a subset of head and neck squamous cell carcinomas, encode three oncogenes: E5, E6, and E7. To determine the oncogenic properties of HPV16 E5 in vivo, we previously generated K14E5 transgenic mice, in which expression of E5 was directed to the basal compartment of stratified squamous epithelia....

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Identifiers

PMID: 17616666
DOI: 10.1158/0008-5472.CAN-07-0921
PMCID: PMC2858287

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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