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Article

A Case-control Study of Major Genetic Predisposition Risk Alleles in Developing DDD in the Northeast US Population: Effects of Gene-gene Interactions.

Spine - 15 Nov 2021

Valtchinov Vladimir I, Zhai Bingxue K, Hida Tomoyuki, Lacson Ronilda, Raja Ali, Hatabu Hiroro, Khorasani Ramin

Abstract excerpt

STUDY DESIGN: A case-control study of risk alleles for degenerative disc disease (DDD) using magnetic resonance (MR) imaging for phenotyping. OBJECTIVE: We aim to provide the first statistically adequately powered study of the relationship between the presence of common risk alleles and occurrence of DDD in Eastern US population. SUMMARY OF BACKGROUND DATA: Many genetic predisposing factors have been identified...

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PMID: 33973562
DOI: 10.1097/BRS.0000000000004104

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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