Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Focal adhesions are essential to drive zebrafish heart valve morphogenesis

11 Jan 2019

Abstract excerpt

Elucidating the morphogenetic events that shape vertebrate heart valves, complex structures that prevent retrograde blood flow, is critical to understanding valvular development and aberrations. Here, we used the zebrafish atrioventricular (AV) valve to investigate these events in real time and at single-cell resolution. We report the initial events of collective migration of AV endocardial cells (ECs) into the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cardiac Valve Diseases and Treatments
Share to Congenital heart defects research
Share to Proteoglycans and glycosaminoglycans research

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 30635353
DOI: 10.1083/jcb.201807175

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Focal adhesions are essential to drive zebrafish heart valve morphogenesisPMID 30635353Read ↗

Integrin α5 and Integrin α4 cooperate to promote endocardial differentiation and heart morphogenesis.Semantic proximity Read ↗

Real-time 3D visualization of cellular rearrangements during cardiac valve formation.Semantic proximity Read ↗

High-speed imaging of developing heart valves reveals interplay of morphogenesis and functionSemantic proximity Read ↗

Nfatc1 Promotes Interstitial Cell Formation During Cardiac Valve Development in ZebrafishSemantic proximity Read ↗

Tbx1 regulates extracellular matrix-cell interactions in the second heart fieldSemantic proximity Read ↗

Fibronectin and integrin alpha 5 play requisite roles in cardiac morphogenesis.Semantic proximity Read ↗

The role of cell adhesion molecules in Drosophila heart morphogenesis: faint sausage, shotgun/DE-cadherin, and laminin A are required for discrete stages in heart development.Semantic proximity Read ↗

Mechanobiology of myofibroblast adhesion in fibrotic cardiac diseaseSemantic proximity Read ↗

Analysis of heart valve development in larval zebrafishSemantic proximity Read ↗

Fibronectin signals through integrin α5β1 to regulate cardiovascular development in a cell type-specific manner.Semantic proximity Read ↗

Integrin α5/fibronectin1 and focal adhesion kinase are required for lens fiber morphogenesis in zebrafish.Semantic proximity Read ↗

Lamb1a regulates atrial growth by limiting excessive, contractility-dependent second heart field addition during zebrafish heart developmentSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.