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The impact of natural selection on health and disease: uses of the population genetics approach in humans

21 Jan 2013

Abstract excerpt

Investigations of the legacy of natural selection in the human genome have proved particularly informative, pinpointing functionally important regions that have participated in our genetic adaptation to the environment. Furthermore, genetic dissection of the intensity and type of selection acting on human genes can be used to predict involvement in different forms and severities of human diseases. We review here...

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PMID: 23789027
DOI: 10.1111/eva.12045

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