Article
Challenges in human genetic diversity: demographic history and adaptation.
Human molecular genetics - 15 Oct 2007
Balaresque Patricia L, Ballereau Stéphane J, Jobling Mark A
Abstract excerpt
Modern human genetic diversity is the result of demographic history, and selective effects that have acted to adapt different populations to their environments. Broad patterns of global diversity are well explained by geography, based on an out-of-Africa model of early human evolution. Genome-wide searches for signals of selection, plus studies of specific candidate loci and candidate phenotypes, have identified...
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