Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Allele-specific imbalance mapping identifies HDAC9 as a candidate gene for cutaneous squamous cell carcinoma.

International journal of cancer - 1 Jan 2014

Fleming Jessica L, Dworkin Amy M, Allain Dawn C, Fernandez Soledad, Wei Lai, Peters Sara B, Iwenofu O Hans, Ridd Katie, Bastian Boris C, Toland Amanda Ewart

Abstract excerpt

More than 3.5 million nonmelanoma skin cancers were treated in 2006; of these 700,000 were cutaneous squamous cell carcinomas (cSCCs). Despite clear environmental causes for cSCC, studies also suggest genetic risk factors. A cSCC susceptibility locus, Skts5, was identified on mouse chromosome 12 by linkage analysis. The orthologous locus to Skts5 in humans maps to 7p21 and 7q31. These loci show copy number...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Allelic Imbalance
Share to Carcinoma, Squamous Cell

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Chromosome Mapping

Share to Genotype

Share to Histone Deacetylases

Share to Polymorphism, Single Nucleotide

Share to Repressor Proteins

Share to Skin Neoplasms

Source

Open in PubMed Open full text

Identifiers

PMID: 23784969
DOI: 10.1002/ijc.28339
PMCID: PMC3831612

Genes

HDAC9

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Allele-specific imbalance mapping identifies HDAC9 as a candidate gene for cutaneous squamous cell carcinoma.PMID 23784969Read ↗

Convergence of congenic mapping and allele-specific alterations in tumors for the resolution of the Skts1 skin tumor susceptibility locus.Semantic proximity Read ↗

Allele-specific imbalance mapping at human orthologs of mouse susceptibility to colon cancer (Scc) loci.Semantic proximity Read ↗

Susceptibility Loci-Associated Cutaneous Squamous Cell Carcinoma Invasiveness.Semantic proximity Read ↗

Combined Kdm6a and Trp53 Deficiency Drives the Development of Squamous Cell Skin Cancer in Mice.Semantic proximity Read ↗

Genomewide single nucleotide polymorphism microarray mapping in basal cell carcinomas unveils uniparental disomy as a key somatic event.Semantic proximity Read ↗

Allelic imbalances and microdeletions affecting the PTPRD gene in cutaneous squamous cell carcinomas detected using single nucleotide polymorphism microarray analysis.Semantic proximity Read ↗

Allele-specific deletions in mouse tumors identify Fbxw7 as germline modifier of tumor susceptibility.Semantic proximity Read ↗

Single nucleotide polymorphism array analysis defines a specific genetic fingerprint for well-differentiated cutaneous SCCs.Semantic proximity Read ↗

Germline Variation Controls the Architecture of Somatic Alterations in TumorsSemantic proximity Read ↗

Molecular characterization of HDAC8 deletions in individuals with atypical Cornelia de Lange syndrome.Semantic proximity Read ↗

Genetic variants in the HLA class II region associated with risk of cutaneous squamous cell carcinoma.Semantic proximity Read ↗

Association between Mutation in SMARCAD1 and Basan Syndrome with Cutaneous Squamous Cell Carcinoma.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.