Effective testing of gene-disease associations.

Article

Effective testing of gene-disease associations.

American journal of human genetics - 1 Aug 1990

Swift M, Kupper L L, Chase C L

Abstract excerpt

We propose a method for testing any hypothesized association between a candidate allele, for which there is a specific laboratory test, and a common chronic disease. Families in which this allele is segregating are identified through index individuals who are homozygous or heterozygous for the al...

Topics

Alleles
Disease Susceptibility
Humans
Likelihood Functions
Models, Genetic

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