Article
Epidemiological evaluation of the use of genetics to improve the predictive value of disease risk factors.
American journal of human genetics - 1 Apr 1995
Khoury M J, Wagener D K
Abstract excerpt
The prevention of common diseases relies on identifying risk factors and implementing intervention in high-risk groups. Nevertheless, most known risk factors have low positive predictive value (PPV) and low population-attributable fraction (PAF) for diseases (e.g., cholesterol and coronary heart disease). With advancing genetic technology, it will be possible to refine the risk-factor approach to target...
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