Article
Epithelial-mesenchymal transition-like events in vulvar cancer and its relation with HPV.
British journal of cancer - 9 Jul 2013
Rodrigues I S, Lavorato-Rocha A M, de M Maia B, Stiepcich M M A, de Carvalho F M, Baiocchi G, Soares F A, Rocha R M
Abstract excerpt
BACKGROUND: Epithelial-to-mesenchymal transition (EMT) still remains an obscure event in vulvar squamous cell carcinoma (VSCC). METHODS: Immunohistochemistry (IHC) expression of E-cadherin, β-catenin, Snail, Slug, Twist and Vimentin was analysed in 87 VSCC, controlled for human papillomavirus (HPV) positivity, considering tumour front and central tumour as different morphological categories from the same tumour....
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