Article
Correlation of epithelial-mesenchymal transition markers with clinicopathologic parameters in adenocarcinomas and squamous cell carcinoma of the lung.
Histology and histopathology - 1 May 2012
Kim Seok-Hyung, Kim Jin Man, Shin Myeong-hee, Kim Chul Woung, Huang Song-Mei, Kang Dong Wook, Suh Kwang Sun, Yi Eunhee S, Kim Kyung-Hee
Abstract excerpt
Epithelial-mesenchymal transition (EMT) is characterized by the loss of epithelial cell junction proteins and the gain of mesenchymal markers. The aim of this study was to analyze the associations between the EMT-related markers vimentin, E-cadherin, β-catenin, slug, snail, and twist1 and clinicopathologic parameters as well as epidermal growth factor receptor (EGFR) gene copy number and protein expression in...
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