Article
Prognostic significance of epithelial-mesenchymal transition phenotypes in upper urinary tract urothelial carcinoma.
Pathology, research and practice - 1 Apr 2018
Cho Junhun, Ha Sang Yun, Kim Seok-Hyung, Sung Hyun Hwan, Kwon Ghee Young
Abstract excerpt
Epithelial-mesenchymal transition (EMT) is a process which epithelial cells gain mesenchymal phenotype such as motility and invasiveness. We investigated the role of EMT in upper urinary tract urothelial carcinoma (UTUC). The patient cohort included 93 cases of UTUC treated with radical nephroureterectomy. Tissue microarrays were constructed from formalin-fixed paraffin-embedded tissue blocks. Immunohistochemical...
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