Association of phosphodiesterase 4 polymorphism (rs702553) with blood pressure in the African American Study of Kidney Disease and Hypertension Genomics Study.

doi:10.1097/FPC.0b013e3283636840

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Association of phosphodiesterase 4 polymorphism (rs702553) with blood pressure in the African American Study of Kidney Disease and Hypertension Genomics Study.

Pharmacogenetics and genomics - 1 Aug 2013

Anthony Ericha G, Richard Erin, Lipkowitz Michael S, Kelley Scott T, Alcaraz John E, Shaffer Richard A, Bhatnagar Vibha

Abstract excerpt

Hypertension is a risk factor for diseases such as stroke, heart and kidney disease. Phosphodiesterase (PDE) enzymes play a significant role in regulating inflammation and there is some association between increased inflammatory cell mediators and development of hypertension. Previous research has shown the single nucleotide polymorphism (rs702553) on the PDE4D gene to be associated with stroke and carotid...

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PMID: 23778321
DOI: 10.1097/FPC.0b013e3283636840

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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