Article
Association of the phosphodiesterase 4D (PDE4D) gene and cardioembolic stroke in an Australian cohort.
International journal of stroke : official journal of the International Stroke Society - 1 Dec 2011
Milton Austin G, Aykanat Verna M, Hamilton-Bruce M Anne, Nezic Mark, Jannes Jim, Koblar Simon A
Abstract excerpt
BACKGROUND: Large-scale epidemiological studies support an important role for susceptibility genes in the pathogenesis of ischemic stroke, with phosphodiesterase 4D identified as the first gene predisposing to ischemic stroke. Several single nucleotide polymorphisms within the phosphodiesterase 4D gene have been implicated in the pathogenesis of stroke. Aim Undertake a multivariate analysis of six single...
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