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Article

Distribution of Killer cell immunoglobulin like receptor genes in end stage renal disease among North Indian population.

Human immunology - 1 Oct 2013

Prakash Swayam, Alam Shahnawaz, Sharma Raj Kumar, Sonawane Avinash, Imran Mohd, Agrawal Suraksha

Abstract excerpt

INTRODUCTION: NK cell function is regulated by cell surface inhibitory and activating receptors including the C-type lectin receptors and Killer Immunoglobulin-like receptors (KIR). The effect of immune modulating cytokines produced by NK cells in the pathogenesis of end stage renal disease (ESRD) remained intriguing. In this regard the present study assesses the combinatorial association of KIR gene content and...

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PMID: 23777934
DOI: 10.1016/j.humimm.2013.06.015

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